Hemolysis attributed to high dose vitamin C: Two case reports

Table 1 Hemoglobin changes during high-dose vitamin C and rescue treatment

Items	Case 1				Case 2				Reference ranges	Units
	Before VC	After VC	Minimum hemoglobin	Post-treatment	Before VC	After VC	Minimum hemoglobin	Post-treatment
RBC	4.81	1.75	1.06	3.54	2.69	1.26	1.16	2.69	4.3-5.8	× 1012/L
HGB	152	63	37	112	96	44	41	86	130-175	g/L
HCT	0.444	0.173	0.105	0.335	0.285	0.144	0.129	0.274	0.40-0.50	L/L
MCV	92.3	98.9	99.1	94.7	105.9	114.8	110.9	101.9	82-100	fL
MCH	31.6	36	34.9	31.6	35.7	35.4	35.2	32	27-34	pg
MCHC	342	364	352	334	2.69	1.26	1.16	2.69	316-354	g/L

VC: Vitamin C; RBC: Red blood cell; HGB: Hemoglobin; HCT: Hematocrit; MCV: Mean corpuscular volume; MCH: Mean corpuscular hemoglobin; MCHC: Mean corpuscular hemoglobin concentration.