Genetically predicted fatty liver disease and risk of psychiatric disorders: A mendelian randomization study

Table 2 Details of variance explained by the selected instruments and F-statistics for the mendelian randomization analysis based on the sample size of autoimmune diseases

Exposure/Outcome	SNPs	R2	F-statistic
Alcohol-related liver disease
Alzheimer’s disease	/	/	/
Anorexia nervosa, anxiety disorder, attention deficit hyperactivity disorder, bipolar disorder, major depressive disorder, multiple disorders, obsessive-compulsive disorder, post-traumatic stress disorder, schizophrenia	rs738408	0.11	57352.08
Non-alcoholic fatty liver disease
Alzheimer’s disease	rs28601761, rs3747207, rs73001065	0.04	35089.81
Anorexia nervosa, anxiety disorder, attention deficit hyperactivity disorder, bipolar disorder, major depressive disorder, multiple disorders, obsessive-compulsive disorder, post-traumatic stress disorder, schizophrenia	rs3747207, rs429358	0.02	26942.59

SNPs: Single nucleotide polymorphisms.