Yiwei Xiaoyu granules for treatment of chronic atrophic gastritis with deficiency syndrome of the spleen and stomach

Table 1 Clinical characteristics of patients before treatment

Characteristics	TG	CG	P value
Age at enrollment (yr)			0.38
≤ 45	6	11
46–55	11	9
≥ 55	19	16
Age, year (mean ± SD)	54.61 ± 10.20	50.06 ± 11.27	0.08
Sex			0.64
Female	18	16
Male	18	20
Kimura–Takemoto classification			0.80
C1	4	4
C2	18	19
C3	13	13
O1	1	0
OLGA stage			0.39
0	0	0
I	14	20
II	14	8
III	6	5
IV	2	3
OLGIM stage			0.63
0	13	17
I	15	13
II	7	6
III	1	0
IV	0	0
Symptom scores of DSSS (mean ± SD)
Abdominal bloating	3.58 ± 0.30	3.42 ± 0.36	0.72
Epigastric pain	2.5 ± 0.39	2.81 ± 0.34	0.55
Loose stools	2.42 ± 0.34	1.83 ± 0.34	0.23
Fatigue	2.14 ± 0.33	2.36 ± 0.38	0.66
Feel weakness of limps	2.36 ± 0.34	3.75 ± 0.30	0.39
Stomach cold	3.25 ± 0.35	3.33 ± 0.34	0.86
Total symptomatic scores	61.5 ± 3.55	57.67 ± 3.98	0.47

CG: Control group; TG: Treatment group; OLGA: Operative Link on Gastritis Assessment; OLGIM: Operative Link on Gastric Intestinal Metaplasia Assessment; DSSS: Deficiency syndrome of the spleen-stomach.