Clinical analysis of colistin sulfate in the treatment of pneumonia caused by carbapenem-resistant Gram-negative bacteria

Table 2 Comparison of total bilirubin, alanine transaminase, aspartate aminotransferase, creatinine, and glomerular filtration rate in both groups

Group	TBIL (μmol/L)	ALT (U/L)	AST (U/L)	Cr (μmol/L)	GFR (mL/min)
Control group (n = 26)
Before treatment	43.4 ± 20.97a	42.35 ± 4.55a	40.29 ± 9.16	78.54 ± 15.67	97.28 ± 23.06
After treatment	23.43 ± 5.28	35.96 ± 3.66	39.88 ± 8.54	85.46 ± 12.67	102.87 ± 30.24
Treatment group (n = 28)
Before treatment	38.92 ± 5.04	46.75 ± 7.43	43.11 ± 7.28	77.89 ± 15.38	92.45 ± 20.33
After treatment	38.26 ± 9.16	41.13 ± 8.75	42.54 ± 10.01	72.34 ± 16,43	98.29 ± 18.98

^aP < 0.05, compared with before treatment.

TBIL: Total bilirubin; ALT: Alanine transaminase; AST: Aspartate aminotransferase; Cr: Creatinine; GFR: Glomerular filtration rate.