Detection and analysis of serum bile acid profile in patients with colonic polyps

Table 6 Bile acid levels in colonic polyps of different sizes (nmol/L)

	Diameter < 1cm group	Diameter ≥ 1 cm group	P value
Primary free BAs
CA	55.80 (22.70, 200.00)	155.00 (32.30, 343.00)	0.005a
CDCA	365.00 (85.20, 835.00)	586.00 (278.00, 1130.00)	0.015a
Primary conjugated BAs
TCA	21.70 (5.50, 46.85)	22.00 (11.50, 75.50)	0.391
GCA	167.00 (84.05, 329.50)	166.00 (57.50, 416.00)	0.927
GCDCA	961.00 (389.00, 1845.00)	900.00 (556.00, 2410.00)	0.333
TCDCA	69.10 (24.05, 152.50)	90.20 (40.70, 262.00)	0.060
Secondary free BAs
DCA	127.00 (21.90, 389.00)	274.00 (77.30, 525.00)	0.063
LCA	5.50 (0.00, 16.15)	8.50 (2.10, 21.60)	0.163
UDCA	64.50 (16.75, 182.50)	196.00 (52.70, 421.00)	0.003a
Secondary conjugated BAs
TDCA	8.20 (0.00, 29.80)	13.30 (3.10, 37.10)	0.317
GDCA	108.00 (12.65, 235.00)	144.00 (10.80, 324.00)	0.610
TLCA	0.00 (0.00, 2.30)	0.80 (0.00, 3.20)	0.189
GLCA	4.60 (0.00, 15.80)	2.50 (0.00, 21.20)	0.736
TUDCA	7.00 (3.00, 15.00)	14.10 (3.90, 34.60)	0.034a
GUDCA	122.00 (42.95, 315.50)	234.00 (59.00, 556.00)	0.030a

^aP < 0.05, there is a statistical difference in this indicator between the two groups.

BA: Bile acid; CA: Cholic acid; CDCA: Chenodeoxycholic acid; TCA: Taurocholic acid; GCA: Glycocholic acid; TCDCA: Taurochenodeoxycholic acid; GCDCA: Glycochenodeoxycholic acid; DCA: Deoxycholic acid; UDCA: Ursodeoxycholic acid; LCA: Lithocholic acid; TDCA: Tauroursodeoxycholic acid; GDCA: Glycodeoxycholic acid; TUDCA: Tauroursodeoxycholic acid; GUDCA: Glycoursodeoxycholic acid; TLCA: Taurolithocholic acid; GLCA: Glycolithocholic acid.