Case Control Study
Copyright ©The Author(s) 2024.
World J Clin Cases. May 6, 2024; 12(13): 2160-2172
Published online May 6, 2024. doi: 10.12998/wjcc.v12.i13.2160
Table 2 Detection results of serum bile acid profiles in the colonic polyp group and the control group (nmol/L)
BA components
Colonic polyp group (n = 204)
Control group (n = 135)
P value
Primary free BAs
        CA62.75 (24.33, 232.00)53.80 (27.60, 149.00)0.571
        CDCA382.50 (105.50, 851.50)294.00 (130.00, 625.00)0.164
Primary conjugated BAs
        TCA21.85 (5.50, 50.50)12.70 (1.50, 32.30)0.015a
        GCA166.50 (76.60, 330.00)126.00 (52.90, 234.00)0.025a
        GCDCA935.50 (430.50, 1967.50)708.00 (298.00, 1250.00)0.005a
        TCDCA74.35 (27.20, 164.50)41.60 (18.30, 119.00)0.006a
Secondary free BAs
        DCA142.00 (30.90, 424.25)234.00 (82.60, 502.00)0.011a
        LCA6.20 (0.13, 17.10)6.40 (0.60, 21.00)0.539
        UDCA73.70 (23.03, 221.50)70.70 (19.00, 199.00)0.545
Secondary conjugated BAs
        TDCA8.50 (0.05, 32.65)7.70 (0.00, 35.30)0.615
        GDCA113.50 (12.08, 248.50)125.00 (34.60, 335.00)0.274
        TLCA0.00 (0.00, 2.40)0.10 (0.00, 4.00)0.255
        GLCA4.60 (0.00, 16.35)5.40 (0.00, 18.10)0.399
        TUDCA7.65 (3.15, 15.00)8.20 (2.50, 15.00)0.369
        GUDCA137.50 (47.25, 343.00)122.00 (63.80, 283.00)0.604
aP < 0.05, there is a statistical difference in this indicator between the two groups.
BA: Bile acid; CA: Cholic acid; CDCA: Chenodeoxycholic acid; TCA: Taurocholic acid; GCA: Glycocholic acid; TCDCA: Taurochenodeoxycholic acid; GCDCA: Glycochenodeoxycholic acid; DCA: Deoxycholic acid; UDCA: Ursodeoxycholic acid; LCA: Lithocholic acid; TDCA: Tauroursodeoxycholic acid; GDCA: Glycodeoxycholic acid; TUDCA: Tauroursodeoxycholic acid; GUDCA: Glycoursodeoxycholic acid; TLCA: Taurolithocholic acid; GLCA: Glycolithocholic acid.