Clinicopathological features and expression of regulatory mechanism of the Wnt signaling pathway in colorectal sessile serrated adenomas/polyps with different syndrome types

Figure 3 Hematoxylin and eosin staining in each group. A and B: Patient with large intestine damp-heat (Da-Chang-Shi-Re) syndrome. A: The crypt epithelium was serrated, and interstitial oedema was observed (× 100); B: Goblet cells were absent in the crypts of the adenoma, and the nuclei were pencil-rod-shaped (× 200). C and D: Patient with spleen-stomach weakness (Pi-Wei-Xu-Ruo) syndrome. C: The epithelium was serrated, and the crypts are evenly distributed and undifferentiated, comprising several goblet cells (× 100); D: The upper part of the crypt was serrated, and the base was not expanded (× 200).