Case Report
Copyright ©The Author(s) 2023.
World J Clin Cases. Mar 16, 2023; 11(8): 1869-1877
Published online Mar 16, 2023. doi: 10.12998/wjcc.v11.i8.1869
Table 3 Etiology, treatment, and prognosis of hyperlactatemia associated with resection of secondary hepatic metastatic carcinoma
Causes of disease
Treatment
Prognosis
Excessive lactic acid productionInsufficient volume leading to inadequate tissue perfusionAggressive fluid replacement to improve tissue perfusionSevere hyperlactatemia is associated with failure of all vital organs and is difficult to reverse with a poor prognosis
Longer hepatic portal block, traumatic injury leading to ischemic reperfusion injuryRehydration, potassium replacement, correction of acidosis
HypothermiaInsulation therapy
Decreased lactate clearanceBlockage of blood flow to the liver leading to a decrease in the liver's ability to remove lactic acidMinimize hepatic portal block time, temperature protectionSevere hyperlactatemia is associated with cardiac surgery, epilepsy and other conditions where the primary condition can be reversed, and has a mild impact on patients with a good prognosis
Impaired liver function associated with surgical resectionHepatoprotective therapy
Impaired kidney functionMaintain circulatory stability and rehydration