IgG4-related kidney disease complicated with retroperitoneal fibrosis: A case report

Figure 2 Histopathological findings on the kidney biopsy. A: The renal interstitium was infiltrated by plasma cells and lymphocytes predominantly with fibrosis like car width [light microscopy: Hematoxylin and eosin (HE), × 100]; B: The injury of the glomerular lesion was mild [light microscopy: Periodic acid-Schiff staining, × 400]; C: Glomerular sclerosis and striate fibrosis in the renal interstitium [light microscopy: Masson and periodic acid-sliver methenamine, × 400]; D: Masson 200 staining of the lesion that was the same as that in Figure A; E and F: Most fusion of glomerular podocytes was observed by electron microscopy, while no electron dense granules were observed in the subepithelium, mesangial area, or subendothelium; G and H: IgG4 plasma cells > 10 cells/high powered field and IgG4 plasma cells/IgG plasma cells > 40% were observed by immunohistochemistry; I: There were CD38-positive plasma cells and CD138-positive plasma cells.