Analysis of differentially expressed genes related to cerebral ischaemia in young rats based on the Gene Expression Omnibus database

Table 6 Gene Ontology functional enrichment analysis of differential genes in young infarcted rats

GO	GO entry	GO description	Number of genes	P value
Biological process	GO:0042493	Drug reaction	6	5.21E-04
	GO:0001975	Response to amphetamine	3	0.001644593
	GO:0001568	Vascular development	3	0.003764749
	GO:0071230	Cellular response to amino acid stimulation	3	0.00430878
	GO:0006469	Negative regulation of protein kinase activity	3	0.007534713
	GO:0010579	Positive regulation of adenylate cyclase activity involved in G protein-coupled receptor signalling	2	0.01174588
	GO:0060158	Phospholipase C activates the dopamine receptor signalling pathway	2	0.01174588
	GO:0007212	Dopamine receptor signalling pathway	2	0.022075774
	GO:1900273	Positive regulation of long-term synaptic potentiation	2	0.023359725
	GO:0070208	Protein heterotrimer	2	0.025922792
	GO:0007190	Activation of adenylate cyclase activity	2	0.028479424
	GO:0051968	Positive regulation of glutamatergic synaptic transmission	2	0.033573445
	GO:0051482	Positive regulation of G protein-coupled cytosolic calcium concentration by phospholipase C activation	2	0.039905051
	GO:0048147	Negative regulation of fibroblast proliferation	2	0.043684948
Cellular composition	GO:0031012	Extracellular matrix	9	4.60E-10
	GO:0005578	Protein, extracellular matrix	7	5.09E-07
	GO:0005581	Collagen trimer	4	5.47E-05
	GO:0005584	Type I collagen trimer	2	0.002482326
	GO:0005861	Troponin complex	2	0.009893989
Molecular function	GO:0004952	Dopamine neurotransmitter receptor activity	2	0.006291172
	GO:0008144	Drug combination	3	0.00881302
	GO:0005515	Protein binding	7	0.011558726
	GO:0035240	Dopamine binding	2	0.013790827
	GO:0046872	Metal ion binding	6	0.025540723

For the convenience of typesetting, Table 6 only shows the enrichment analysis results of some important GO functions. GO: Gene Ontology.