Hidrotic ectodermal dysplasia in a Chinese pedigree: A case report

Figure 2 Region of GJB6. A: Region of GJB6 derived from the proband showing a heterozygous missense mutation 263G→A (arrow) in GJB6; B: Sequence analysis of the same region of GJB6 from a normal individual; C: Real-time reverse transcriptase-polymerase chain reaction results of the expression level of GJB6 mRNA (^aP < 0.01 compared with the blank control and NC control groups; ^bP < 0.01 compared with the GJB6 overexpression group); D: Western blot results of the protein expression level of GJB6 (^aP < 0.01 compared with the blank control and NC control groups; ^bP < 0.01 compared with the GJB6 overexpression group).