Hidrotic ectodermal dysplasia in a Chinese pedigree: A case report

Figure 1 The proband. A: Genealogical analysis of a Chinese family with hidrotic ectodermal dysplasia. Normal individuals are shown as clear circles (females) or squares (males), and affected individuals are shown as solid symbols. Deceased individuals are shown with a slash. The arrow indicates the proband; B: The proband (IV4) had thickening and yellowing of all fingernails; C: The proband had thickening and yellowing of all toenails; D: The proband had yellow patches visible on the soles of the feet; E: The proband had mild keratinization visible on the palm of the hand; F: The degree of palmar toe keratinization decreased in severity in the subsequent generations.