Postoperative jaundice related to UGT1A1 and ABCB11 gene mutations: A case report and literature review

Figure 4 Histopathological biopsy of the liver. The portal area was enlarged to varying degrees, with hyperplasia of fibrous tissue, infiltration of a moderate amount of lymphocytes and a small number of plasma cells, minor bile duct damage, fibrosis around a small number of small bile ducts, and mild bile duct hyperplasia, mild edema of hepatocytes, a few balloon-like degenerated hepatocytes, a few glycogenuclear hepatocytes, bulicular and microbulicular steatosis of hepatocytes (hepatic steatosis cells < 5%), irregular distribution, rare punctate necrosis. Some hepatocytes cholestatic pigment granules can be seen, and some bile ducts are dilated and cholestatic. Yellow arrow: Cholestatic pigment particles; Black triangle: Hepatocyte adipose change. A: Hematoxylin-eosin (HE) (× 1); B: HE (× 4); C: HE (× 10); D: HE (× 40).