Functioning gonadotroph adenoma with hyperestrogenemia and ovarian hyperstimulation in a reproductive-aged woman: A case report and review of literature

Table 1 Biochemical investigations before and after pituitary surgery

Biochemicals	Normal values	Before surgery	After surgery	After surgery	After surgery
			1 d	1 mo	3 mo
Estradiol (pg/mL)	FP:12.5-166, LP:43.8-211	6977	53.7	39.5	69.1
FSH (mIU/mL)	FP:3.5-12.5, LP:1.7-7.7	2.3	1.8	8.5	7.9
LH (mIU/mL)	FP:2.4-12.6, LP:1.0-11.4	3.8	0.6	3.8	3.2
PRL (uIU/mL)	102-496	65.87	33.26	550.3	59.28
PROG (ng/mL)	FP:0.057-0.893, LP:1.83-23.9	21.98	0.14	0.26	0.42
GH (pg/mL)	126-9880	463.1	438.1	158.7	336
Testosterone (ng/mL)		0.69	0.06	0.11	0.05
ACTH (pmol/L)	1.6-13.9	4.79			4.48
CA125 (U/mL)	< 35	41.6			14.2
AMH (ng/mL)	2.06-6.98	3.06			1.58
PTH (pmol/L)	1.27-9.33	3.55			3.82
FT4 (pmol/L)	6.44-18.02	10.34			13.32
TSH (µIU/mL)	0.35-5.1	1.46			2.126
Cortisol (nmol/L)	6-10 am:133-537	404

FP: Follicular phase; LP: Luteal phase; FSH: Follicle-stimulating hormone; LH: Luteinizing hormone; PRL: Prolactin; PROG: Progesterone; GH: Growth hormone; ACTH: Adrenocorticotropic hormone; AMH: Anti-Müllerian hormone; PTH: Parathyroid hormone; FT4: Free T4; TSH: Thyroid-stimulating hormone; Pituitary surgery: transsphenoidal resection of pituitary macroadenoma.