Case Report
Copyright ©The Author(s) 2023.
World J Clin Cases. Feb 16, 2023; 11(5): 1206-1216
Published online Feb 16, 2023. doi: 10.12998/wjcc.v11.i5.1206
Table 2 Timeline of clinical history
Date
Event
2011Breast cancer (right mastectomy and lymphadenectomy + adjuvant chemotherapy with cyclophosphamide, methotrexate, 5-fluorouracil + hormone therapy with tamoxifen)
2020Pancreatic cancer with hepatic metastases (chemotherapy with nab-paclitaxel and gemcitabine)
February 2021Second-line treatment with 5-fluorouracil, folic acid, oxaliplatin, irinotecan
May 2021Deep vein thrombosis (right external iliac vein and both common femoral veins) and pulmonary embolism
Start LMWH
June 2021Persistence of deep vein thrombosis and pulmonary embolism
LMWH replaced with edoxaban for inefficacy and patient’s preference
August 2021Chemotherapy with carboplatin for worsening of liver metastases
September 2021Dyspnea at rest and fatigue
Echocardiogram: Incidental large right atrial mass, highly mobile and not vascularized, close to the ICV orifice
Edoxaban replaced with LMWH due to thrombocytopenia and anemia
October 2021Halved LMWH dose due to further platelet count decrease
November 2021Marked decline of clinical general condition
Discontinuation of anticancer drugs for severe disease progression
Discontinuation of LMWH for severe thrombocytopenia
Start palliative care