Major depressive disorders in patients with inflammatory bowel disease and rheumatoid arthritis

doi:10.12998/wjcc.v11.i4.764

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World Journal of Clinical Cases

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Feb 6, 2023; 11(4): 764-779
Published online Feb 6, 2023. doi: 10.12998/wjcc.v11.i4.764

Table 1 Comorbidities comparison in inflammatory bowel disease-rheumatoid arthritis overlap patients with and without major depressive disorders, national inpatient sample year 2000 to 2019

	IBD-RA without depressive disorders, weighted, n (%)	IBD-RA with depressive disorders, weighted, n (%)	P value
Liver disease, mild	6400 (5.97)	2130 (8.14)	< 0.0001^a
Liver disease, moderate to severe	786 (0.73)	230 (0.88)	0.2871^a
Peptic ulcer disease	1709 (1.59)	632 (2.41)	< 0.0001^a
Esophageal disorders	30712 (28.65)	10569 (40.40)	< 0.0001^a
Gastritis	3781 (3.52)	1124 (4.30)	0.0095^a
Diabetes mellitus with chronic complications	6367 (5.94)	2005 (7.66)	< 0.0001^a
Diabetes mellitus without chronic complications	14014 (13.07)	3533 (13.50)	0.4244^a
Hypertension	40782 (38.05)	10493 (40.12)	0.0080^a
Heart Failure	12798 (11.94)	2908 (11.11)	0.1176^a
Coronary artery disease	16644 (15.53)	3549 (13.57)	0.0007^a
Cardiac dysrhythmias	16114 (15.04)	3299 (12.61)	< 0.0001^a
Myocardial infarction	1316 (1.23)	224 (0.86)	0.0237^a
Stroke	1530 (1.42)	230 (0.88)	0.0018^a
Iron Deficiency Anemia	9298 (8.68)	2296 (8.78)	0.8167^a
Nutritional deficiencies	4062 (3.79)	1494 (5.71)	< 0.0001^a
Lipid Metabolism disorders	24990 (23.32)	7036 (26.90)	< 0.0001^a
Thyroid disorders	18029 (16.82)	5531 (21.15)	< 0.0001^a
Chronic Pancreatitis	1165 (1.09)	507 (1.94)	< 0.0001^a
Renal failure, moderate	8563 (7.99)	2132 (8.15)	0.7113^a
Renal failure, severe	2965 (2.77)	767 (2.93)	0.5434^a
Menopausal disorders	536 (0.50)	222 (0.84)	0.0033^a
Osteoporosis	11752 (10.97)	3544 (13.55)	< 0.0001^a
Osteoarthritis	15084 (14.07)	4562 (17.44)	< 0.0001^a
Obesity	11706 (10.92)	4062 (15.53)	<.0001¹
Weight Loss	1201 (1.12)	365 (1.39)	0.1101^a
Protein-calorie malnutrition	8479 (7.91)	2370 (9.06)	0.0085^a
Leukemia	558 (0.52)	134 (0.51)	0.9401^a
Lymphoma	838 (0.78)	181 (0.69)	0.5132^a
Metastatic cancer	1381 (1.29)	329 (1.26)	0.8524^a
Solid tumor without metastasis, malignant	3785 (2.84)	850 (0.64)	0.8524^a
Paralysis	1498 (1.40)	495 (1.89)	0.0114^a
Dementia	2291 (2.14)	886 (3.39)	< 0.0001^a
AIDS	212 (0.19)	45 (0.17)	0.6818^a
Smoking	32336 (30.17)	9893 (37.82)	< 0.0001^a
Alcohol	1747 (1.63)	950 (3.63)	< 0.0001^a
Opioids	3180 (2.97)	1797 (6.87)	< 0.0001^a

^aRao-Scott Chi-Square 2-tailed Test for the association of two Categorical Variables.

IBD-RA: Inflammatory bowel disease-rheumatoid arthritis; AIDS: Acquired immunodeficiency syndrome.

Citation: Haider MB, Basida B, Kaur J. Major depressive disorders in patients with inflammatory bowel disease and rheumatoid arthritis. World J Clin Cases 2023; 11(4): 764-779
URL: https://www.wjgnet.com/2307-8960/full/v11/i4/764.htm
DOI: https://dx.doi.org/10.12998/wjcc.v11.i4.764