Impact of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers on the mortality in sepsis: A meta-analysis

Table 2 Stratified analysis of the premorbid calcium channel blockers and mortality of sepsis according to study characteristics

Group	No. of studies	OR (95%CI)	Pheterogeneity	I2 (%)
Geographic area
Non-Asia	4	0.91 (0.74-1.09)	0	94.6
Asia	4	0.94 (0.91-0.98)	0	96.7
Object
ACEIs	2	0.94 (0.89-0.99)	< 0.01	95.3
ARBs	3	0.84 (0.79-0.88)	0.006	80.7
ACEIs/ARBs	3	1.31 (1.23-1.39)	0.983	0
NOS
6	3	0.88 (0.85-0.91)	0	88.6
7	5	1.31 (1.24-1.39)	0.013	68.4

ACEI: Angiotensin-converting enzyme inhibitors; ARB: Angiotensin receptor blocker; OR: Odds ratio; NOS: Newcastle-ottawa scale.