Immunotherapy in SMARCB1 (INI-1)-deficient sinonasal carcinoma: Two case reports

Figure 3 Histopathological and immunohistochemical features of Case 2. A and B: Tumor cells had no clear differentiation, glandular morphology and mucoid interstitial substance could be observed in some areas. (Hematoxylin and eosin staining, ×200); C-J: The tumor cells were diffuse positivity for CK(x100), CK8/18 (×100), partial positivity for P40 (×100), P63 (×100), S-100 (×100), Syn (×100), and negativity for CK7 (×100), LCA (×100); K: Tumors had a PD-L1 combined positive score of one (×100); L: The Ki-67 proliferative index was approximately 70% (×100).