Immunotherapy in SMARCB1 (INI-1)-deficient sinonasal carcinoma: Two case reports

Figure 2 Histopathological and immunohistochemical features of Case 1. A: Tumor cells grew as nested (hematoxylin and eosin staining, ×200); B and C: The tumor cells were positive for creatine-kinase (×100) and negative for S-100 (×100); D: The Ki-67 proliferative index was approximately 70% (×100); E: INI-1 expression was present in the nuclei of surrounding non-neoplastic cells but completely absent in the tumor cells (×100).