Efficacy and safety of laparoscopic vs open gastrectomy after neoadjuvant therapy for locally advanced gastric cancer

Table 2 Perioperative outcomes of the two groups

Variable	LG group (n = 38)	OG group (n = 38)	P value
Operation time (min)	210 ± 45	220 ± 50	0.28
Blood loss (mL)	100 ± 50	300 ± 100	< 0.001
R0 resection rate (%)	36 (94.7)	35 (92.1)	0.64
Number of harvested lymph nodes1	22 ± 8	23 ± 9	0.57
Proximal margin (cm)2	3.5 ± 1.2	3.6 ± 1.3	0.72
Distal margin (cm)3	4.2 ± 1.4	4.3 ± 1.5	0.79
Hospital stay (days)4	10 ± 3	15 ± 4	< 0.001
Anastomotic leakage-Grade I-IIA5 (%)	2 (5.3)	3 (7.9)	0.67
Anastomotic leakage-Grade IIB-IVB5 (%)	0	1 (2.6)
Intra-abdominal abscess-Grade I-IIA5 (%)	1 (2.6)	2 (5.3)	0.54
Intra-abdominal abscess-Grade IIB-IVB5 (%)	0	1 (2.6)
Wound dehiscence-Grade I-IIA5 (%)	1 (2.6)	2 (5.3)	0.73
Wound dehiscence-Grade IIB-IVB5	0	0
Surgical site infection-Grade I-IIA5 (%)	2 (5.3)	8 (21.1)	0.04
Surgical site infection-Grade IIB-IVB5	0	0
Other complications-Grade I-IIA5 (%)	4 (10.5)	5 (13.2)	0.47
Other complications-Grade IIB-IVB5	0	1 (2.6)

¹Only for patients who underwent D2 lymphadenectomy.

²Only for patients who underwent total gastrectomy.

³Only for patients who underwent subtotal gastrectomy.

⁴From the day of surgery to the day of discharge.

⁵According to the Clavien-dindo classification.

LG: Laparoscopic gastrectomy; OG: Open gastrectomy.