Qixue Shuangbu decoction and acupuncture combined with Western medicine in acute severe stroke patients

Table 4 Comparison of calcitonin gene-related peptide, ubiquitin carboxyl-terminal hydrolase 1, tumor necrosis factor-α, interleukin-2, interleukin-8 between and within groups (mean ± SD)

Indicators	Time	Control group (n = 34)	Observation group (n = 34)	t value	P value
CGRP (pg/mL)	Before treatment	21.52 ± 5.36	20.97 ± 5.71	0.409	0.683
	After treatment	28.26 ± 6.17a	36.58 ± 6.78a	5.292	0.000
UCH-L1 (µg/L)	Before treatment	0.40 ± 0.18	0.41 ± 0.13	0.263	0.794
	After treatment	0.25 ± 0.11a	0.17 ± 0.10a	3.138	0.003
TNF-α (pg/mL)	Before treatment	44.52 ± 5.89	42.97 ± 6.01	1.074	0.287
	After treatment	21.02 ± 4.15a	14.63 ± 3.85a	6.582	0.000
IL-2 (pg/mL)	Before treatment	15.89 ± 2.16	15.81 ± 2.24	0.150	0.881
	After treatment	10.13 ± 1.92a	6.78 ± 1.52a	7.977	0.000
IL-8 (pg/mL)	Before treatment	5.23 ± 0.82	5.18 ± 0.91	0.238	0.813
	After treatment	4.64 ± 0.53a	3.47 ± 0.42a	10.088	0.000

^aP < 0.05 vs before treatment.

CGRP: Calcitonin gene-related peptide; UCH-L1: Ubiquitin carboxyl-terminal hydrolase 1; TNF-α: Tumor necrosis factor-α; IL: Interleukin.