Effect of T-regulatory cells and interleukin-35, interleukin-10, and transforming growth factor-beta on diffuse large B-cell lymphoma

Table 1 Serum expression levels of interleukin (IL)-35, IL-10, transforming growth factor beta across the subgroups

Group	n	IL-35 (pg/mL)	IL-10 (pg/mL)	TGF-β (pg/mL)
Incipient	79	166.79 ± 132.69	38.31 ± 30.92	653.3 ± 610.26
Effectively treated	45	115.8 ± 81.47	26.55 ± 18.75	602.5 ± 709.82
Relapse-refractory	34	234.29 ± 156.62	53.87 ± 36.79	720.54 ± 447.53
Control	30	107.34 ± 66.6	24.57 ± 20.25	416.69 ± 339.78
F value		8.47c	7.562c	1.686
P value		< 0.001	< 0.001	0.172
Multiple comparison		Expression levels of IL-35 in both the incipient and relapsed-refractory groups were higher than those in the effectively treated and normal control groups	Expression levels of IL-10 in the incipient and relapse-refractory groups were higher than effective therapy and normal control groups	/

^cIndicates the use of Welch’s analysis of variance (i.e., McDonald reported that analysis of variance) test.

Data presented mean ± SD unless otherwise indicated. IL-35: Interleukin-35; IL-10: Interleukin-10; TGF-β: Transforming growth factor beta.