Axenfeld-Reiger syndrome: A search for the missing links

Table 4 Anterior segment findings in cases of Axenfeld-Rieger syndrome based on slit-lamp biomicroscopy (N = 10)

Sr. No.	Corneal abnormalities		Iris tissue abnormalities						Associated ocular features
	Posterior embryotoxon		Corectopia		Polycoria		Iris hypoplasia
	RE	LE	RE	LE	RE	LE	RE	LE
Case 1	+	+	+	+	+	+	+	-	LSCD BE, PAS on Gonioscopy BE
Case 2	NA	+	NA	-	NA	-	NA	+	Corneal oedema, Nystagmus, Aniridia LE
Case 3	+	+	-	+	-	+	-	-	Mature cataract LE, 360° NVI LE
Case 4	+	-	-	+	-	+	-	-	BE cobblestone papillae with RE Shield’s Ulcer s/o VKC, Cornea Plana, Corneal oedema BE
Case 5	+	+	-	-	-	-	-	-	-
Case 6	+	+	-	-	-	-	-	-	-
Case 7	+	+	-	-	-	-	-	-	BE Corneal Haze
Case 8	+	+	-	-	-	+	-	-	Nystagmus, LE Large Surgical PI, Well-formed functioning bleb BE
Case 9	+	+	+	+	+	+	+	+
Case 10	+	+	+	+	+	+	+	+

BCVA: Best Corrected Visual Acuity; IOP: Intraocular Pressure; RE: Right eye; LE: Left eye; BE: Both eyes; LSCD: Limbal Stem Cell Deficiency; PAS: Peripheral Anterior Synechiae; PI: Peripheral iridectomy; NVI: Neovascularization of iris; s/o: Suggestive of; VKC: Vernal keratoconjunctivitis; NRR: Neuroretinal rim.