Axenfeld-Reiger syndrome: A search for the missing links

Table 2 Symptoms and treatment history of cases of Axenfeld-Rieger syndrome (N = 10)

Case No.	Symptoms	Duration	Previous treatment (in both eyes)	Symptomatic	Diagnosed on active search
Case 1	Decreased vision	2 yr	Eye Drop Travoprost 0.004% HS; Eye Drop Brimonidine 0.2% + Timolol 0.5% BD; Eye Drop Dorzolamide 2% TDS	Yes	No
	Photophobia	2 mo
	Pain	2 mo
	Watering	2 mo
Case 2	Decreased vision in left eye	Since childhood	None	Yes	Yes
	Right eye lost to trauma	3 yr
Case 3	Decreased vision in both eyes	Since childhood	None	Yes	No
Case 4	Burning sensation and itching in both eyes	1 yr	Eye drop Travoprost 0.004% HS; Eye drop Brimonidine 0.2% + Timolol 0.5% BD	Yes	Yes
Case 5	None	NA	None	No	Yes
Case 6	None	NA	None	No	Yes
Case 7	Blinking, crying and watering of both eyes on exposure to light	8 mo	None	Yes	No
Case 8	Decreased vision in both eyes	15 yr	Trabeculectomya	Yes	No
Case 9	None; Diagnosed glaucoma in both eyes	17 yr	Eye drop Brimonidine 0.2% BD	Yes	No
Case 10	Decreased vision in both eyes	5 yr	Eye drop Brimonidine 0.2% + 0.5% Timolol BD	Yes	Yes

^aNo documents pertaining to this surgery were available for review.

HS: At night; BD: Twice daily; TDS: Thrice daily; NA: Not applicable.