Hyperprogression after anti-programmed death-1 therapy in a patient with urothelial bladder carcinoma: A case report

Table 1 multiple genetic alterations

Gene	Genetic variation information	Gene mutation abundance
TP53	p.R273H 8 Exon	31.56%
MST1R	p.A1301G 19 Exon	8.82%
WWTR1	p.Q233del 4 Exon	3.54%
KMT2D	p.P4949fs 48 Exon	17.82%
	p.P4055fs 39 Exon	8.00%
	p.T698A 10 Exon	9.48%
CDK8	p.Q377del 12 Exon	2.91%
PTPRT	p.V769E 15 Exon	0.99%
GNAS	p.R844H 8 Exon	1.69%