Randomized controlled trial on the efficacy and safety of autologous serum eye drops in dry eye syndrome

Table 2 Changes in ocular surface disease index score and other secondary outcomes from baseline to week 12

Variable	ASEDs group (n = 116)	Artificial tears group (n = 116)	P value
OSDI score	-26.4 ± 9.8 (-38%)	-16.1 ± 8.9 (-19%)	< 0.001
TBUT (s)	+2.4 ± 1.3 (+75%)	+0.6 ± 0.9 (+18%)	< 0.001
Schirmer I test (mm/5 min)	+4.6 ± 2.4 (+135%)	+1.5 ± 1.8 (+43%)	< 0.001
CFS score	-3.4 ± 1.8 (-51%)	-1.9 ± 1.6 (-28%)	< 0.001
CIC score	-1.2 ± 0.5 (-57%)	-0.5 ± 0.4 (-23%)	< 0.001

Data are presented as mean ± SD and percentage change in parentheses. ASEDs: Autologous serum eye drops; OSDI: Ocular surface disease index; TBUT: Tear break-up time; CFS: Corneal fluorescein staining; CIC: Conjunctival impression cytology.