Laparoscopic vs open radical resection in management of gallbladder carcinoma: A systematic review and meta-analysis

Table 1 Publication bias test of major measured outcomes

	No. of studies	No. of patients		Egger's test		Begg's test (continuity corrected)
		LRR	ORR	t	P > |t|	z	P > |z|
No. LNH	17	799	1209	-5.1	< 0.001	0.37	0.711
Operation time	16	564	764	1.57	0.139	0.86	0.392
Blood loss	14	489	689	-2.18	0.050	1.86	0.063
POLS	17	799	1209	-3.03	0.008	0.04	0.967
R0 rate	8	1609	1705	1.64	0.162	0.00	1.000
Complications	15	511	703	-1.67	0.119	1.29	0.198
Complications (Clavien-Dindo 3-4)	8	244	245	-1.85	0.162	0.73	0.462
OS	15	1299	1936	0.3	0.767	0.68	0.499
TFS	10	339	338	-1.04	0.329	0.36	0.721

No. LNH: Number of lymph node harvested; POLS: Postoperative length of stay; OS: Overall survival; TFS: Tumor-free survival; LRR: Laparoscopic radical resection; ORR: Open radical resection.