Effect of polyene phosphatidylcholine/ursodeoxycholic acid/ademetionine on pregnancy outcomes in intrahepatic cholestasis

Table 4 Liver enzyme indices and liver function before and after the treatment (mean ± SD)

Groups	ALT (U/L)		AST (U/L)
	Before the treatment	After the treatment	Before the treatment	After the treatment
Control (n = 300)	86.15 ± 4.45	46.96 ± 3.08a	80.84 ± 5.05	34.68 ± 2.94a
Combined (n = 300)	86.48 ± 4.92	31.01 ± 2.15a	81.02 ± 4.98	29.05 ± 2.03a
t value	0.416	35.527	0.212	13.184
P value	0.678	< 0.001	0.832	< 0.001
	TB (µmol/L)		CG (µg/L)
Control (n = 300)	27.56 ± 6.37	17.68 ± 5.98a	2718.00 ± 280.17	887.21 ± 88.74a
Combined (n = 300)	27.48 ± 6.18	11.43 ± 3.37a	2754.00 ± 253.48	729.81 ± 65.46a
t value	0.075	7.618	0.797	11.942
P value	0.940	< 0.001	0.427	< 0.001

^aP < 0.05 between before and after treatment in one group, indicates a statistically significant difference.

ALT: Aalanine aminotransferas; AST: Aspartate aminotransferase.