Unveiling the hidden world of gut health: Exploring cutting-edge research through visualizing randomized controlled trials on the gut microbiota

Table 5 The ten most-cited articles that cited research involving randomized controlled trials on gut microbiota between 2003 and 2022

Ref.	Title	Year	Source title	Cited by	Impact index per article1
Vrieze et al[89], 2012	“Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome”	2012	Gastroenterology	1977	171.0
Moayyedi et al[85], 2015	“Fecal Microbiota Transplantation Induces Remission in Patients With Active Ulcerative Colitis in a Randomized Controlled Trial”	2015	Gastroenterology	1012	116.3
Wu et al[90], 2017	“Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug”	2017	Nature Medicine	892	137.3
Subramanian et al[88], 2014	“Persistent gut microbiota immaturity in malnourished Bangladeshi children”	2014	Nature	773	89.7
Paramsothy et al[86], 2017	“Multidonor intensive fecal microbiota transplantation for active ulcerative colitis: A randomised placebo-controlled trial”	2017	The Lancet	754	118.3
Gareau et al[82], 2010	“Probiotics and the gut microbiota in intestinal health and disease”	2010	Nature Reviews Gastroenterology and Hepatology	596	43.5
Cani et al[81], 2009	“Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal”	2009	American Journal of Clinical Nutrition	534	36.6
Queipo-Ortuño et al[87], 2012	“Influence of red wine polyphenols and ethanol on the gut microbiota ecology and biochemical biomarkers”	2012	American Journal of Clinical Nutrition	481	41.7
Lee et al[84], 2016	“Frozen vs fresh fecal microbiota transplantation and clinical resolution of diarrhea in patients with recurrent clostridium difficile infection a randomized clinical trial”	2016	JAMA-Journal of the American Medical Association	461	62.3
Ianiro et al[83], 2018	“Randomised clinical trial: Faecal microbiota transplantation by colonoscopy vs. vancomycin for the treatment of recurrent Clostridium difficile infection”	2015	Alimentary Pharmacology and Therapeutics	414	47.8

¹The impact index per article is presented based on Reference Citation Analysis (Source: Baishideng Publishing Group Inc. Pleasanton, CA 94566, United States).