Predictive value of preoperative albumin-bilirubin score and other risk factors for short-term outcomes after open pancreatoduodenectomy

Table 6 Factors associated with postoperative mortality (univariate logistic regression), n (%)

	Survived (n = 329)	Died (n = 18)	OR (95%CI)	P value
Male gender	182 (55.3)	11 (61.1)	1.27 (0.48-3.36)	0.631
Age (yr), median (IQR)	68 (61-75)	75.5 (69-82)	1.07 (1.01-1.14)	0.015
BMI, median (IQR)	25 (22.5-28.4)	27.7 (24.9-29.7)	1.07 (0.96-1.19)	0.223
ASA score				0.5201
1	10 (3)	0 (0)
2	129 (39.2)	7 (38.9)
3	188 (57.1)	9 (50.0)
4	2 (0.6)	2 (11.1)
ALBI score	-2.6 (-3.0 to -2.0)	-2.8 (-3.1 to -1.8)	1.18 (0.59-2.34)	0.639
Operation type
PPPD	168 (51.1)	7 (38.9)	1
Whipple	161 (48.9)	11 (61.1)	1.64 (0.62-4.33)	0.319
Somatostatin use	178 (54.1)	7 (38.9)	0.54 (0.20-1.43)	0.214
Soft pancreatic texture	152 (52.2)	12 (75.0)	2.74 (0.86-8.71)	0.087
Blood loss (mL), median (IQR)	400 (250-500)	600 (400-1000)	1.07 (1.02-1.13)	0.007
Pathology
Pancreatic carcinoma	164 (49.8)	6 (33.3)	0.50 (0.18-1.37)	0.180
Bile duct carcinoma	32 (9.7)	4 (22.2)	2.65 (0.82-8.54)	0.102
Duodenal carcinoma	9 (2.7)	0 (0)		0.324*
Ampullary carcinoma	42 (12.8)	4 (22.2)	1.95 (0.61-6.21)	0.257
NET	26 (7.9)	1 (5.6)	0.69 (0.09-5.36)	0.719
IPMN	15 (4.6)	1 (5.6)	1.23 (0.15-9.88)	0.845

¹Likelihood ratio test.

OR: Odds ratio; IQR: Interquartile range; BMI: Body mass index; ALBI: Albumin-bilirubin; ASA score: American Society of Anesthesiologists score; PPPD: Pylorus-preserving pancreatoduodenectomy; NET: Neuroendocrine tumour; IPMN: Intraductal papillary mucinous neoplasm.