Predictive value of preoperative albumin-bilirubin score and other risk factors for short-term outcomes after open pancreatoduodenectomy

Table 3 Factors associated with major postoperative complications (univariate logistic regression), n (%)

	No or minor postoperative complications (n = 252)	Major postoperative complications (n = 95)	OR (95%CI)	P value
Male gender	130 (51.6)	63 (66.3)	1.85 (1.13-3.02)	0.014
Age (yr), median (IQR)	68 (61-76)	69 (63-76)	1 (0.98-1.03)	0.698
BMI, median (IQR)	24.8 (22.3-27.9)	26.6 (23.1-29.8)	1.07 (1.02-1.13)	0.012
ASA score
1	9 (3.6)	1 (1.1)	1
2	98 (38.9)	38 (40)	3.49 (0.43-28.49)	0.243
3	144 (57.1)	53 (55.8)	3.31 (0.41-26.78)	0.261
4	1 (0.4)	3 (3.2)	27 (1.26-578.35)	0.035
ALBI score	-2.6 (-3.0 to -2.0)	-2.6 (-3.0 to -1.9)	1.26 (0.89-1.78)	0.188
Operation type
PPPD	131 (52)	44 (46.3)	1
Whipple	121 (48)	51 (53.7)	1.25 (0.78-2.01)	0.347
Somatostatin use	130 (51.6)	55 (57.9)	1.29 (0.80-2.08)	0.294
Soft pancreatic texture	103 (46.2)	61 (72.6)	3.09 (1.79-5.34)	< 0.001
Blood loss (mL), median (IQR)	400 (250-500)	400 (300-700)	1.08 (1.02-1.14)	0.005
Pathology
Pancreatic carcinoma	136 (54.0)	34 (35.8)	0.48 (0.29-0.77)	0.003
Bile duct carcinoma	22 (8.7)	14 (14.7)	1.81 (0.88-3.70)	0.105
Duodenal carcinoma	2 (0.8)	7 (7.4)	9.94 (2.03-48.77)	0.005
Ampullary carcinoma	36 (14.3)	10 (10.5)	0.71 (0.34-1.49)	0.359
NET	18 (7.1)	9 (9.5)	1.36 (0.59-3.14)	0.471
IPMN	11 (4.4)	5 (5.3)	1.22 (0.41-3.60)	0.722

OR: Odds ratio; IQR: Interquartile range; BMI: Body mass index; ALBI: Albumin-bilirubin; ASA score: American Society of Anesthesiologists score; PPPD: Pylorus-preserving pancreatoduodenectomy; NET: Neuroendocrine tumour; IPMN: Intraductal papillary mucinous neoplasm.