Rare ROS1-CENPW gene in pancreatic acinar cell carcinoma and the effect of crizotinib plus AG chemotherapy: A case report

doi:10.12998/wjcc.v11.i24.5823

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Aug 26, 2023 (publication date) through Nov 23, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Aug 26, 2023; 11(24): 5823-5829
Published online Aug 26, 2023. doi: 10.12998/wjcc.v11.i24.5823

Table 2 Somatic mutation results

Gene	Transcript	Nucleobase alternation	Amino acid alternation	Functional domain	Mutation frequency
KRAS	NM_033360.2	c.34G>C	p.G12R	EX2	52.7%
PIK3R2	NM_005027.2	c.443C>T	p.P148L	EX4	18.0%
TP53	NM_000546.5	c.797G>T	p.G266V	EX8	15.1%
TGFBR2	NM_001024847.2	c.1528_1532delGAAAG	p.E510Hfs*29	EX7	15.0%
CDKN2A	NM_000077.4	c.35C>A	p.S12*	EX1	13.9%

Citation: Wang T, Shen YY. Rare ROS1-CENPW gene in pancreatic acinar cell carcinoma and the effect of crizotinib plus AG chemotherapy: A case report. World J Clin Cases 2023; 11(24): 5823-5829
URL: https://www.wjgnet.com/2307-8960/full/v11/i24/5823.htm
DOI: https://dx.doi.org/10.12998/wjcc.v11.i24.5823