Case Report
Copyright ©The Author(s) 2023.
World J Clin Cases. Aug 26, 2023; 11(24): 5804-5810
Published online Aug 26, 2023. doi: 10.12998/wjcc.v11.i24.5804
Table 2 Histopathological and immunohistochemical features of 10 cases
Case
Intraepidermal nests
Sharp delineation
Hyperkeratosis or acanthotic epidermis
Invasive growth
Nuclear and cytoplasmic pleomorphisms
Mitotic figure
Ductal structure
Immunohistochemistry
1(+)(-)(+)(+)(-)(+)(+)EMA (+), CK10 (+), CK14(+)
2(+)(+)(-)(-)(-)(+)(-)EMA (+), CEA (+)
3(+)(+)(+)(+)(+)(+)(+)NR
4(+)(+)(+)(-)(-)(-)(+)NR
5(+)(+)(+)(-)(+)(+)(+)CK5/6 (+), P63 (+), CEA (-) CK7 (-)
6(+)(+)(+)(-)(+)(+)(+)CytokeratinAE1/3 (+), EMA (+), CEA (+), CK7 (+)
7(+)(+)(+)(-)(+)(+)(+)CAM5.2 (+), CEA (+), S100 (+), EMA (+)
8(+)(+)(+)(+)(+)(+)(-)NR
9(+)(+)(+)(+)(+)(-)(-)EMA (+), CEA (+), S100 (+)
10(+)(+)(-)(-)(+)(-)(-)NR
EMA: Epithelial membrane antigen; CEA: Carcinoembryonic antigen; CK10: Cytokeratin10; CK14: Cytokeratin 14; CK5/6: Cytokeratin 5/6; CK7: Cytokeratin 7; CK19: Cytokeratin 19; P63: Transformation-related protein 63; CAM5.2: Cytokeratin CAM5.2; S100: S100 proteins; NR: Not reported; (+): Positive; (-): Negative.