Effect of vitamin supplementation on polycystic ovary syndrome and key pathways implicated in its development: A Mendelian randomization study

doi:10.12998/wjcc.v11.i23.5468

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Aug 16, 2023; 11(23): 5468-5478
Published online Aug 16, 2023. doi: 10.12998/wjcc.v11.i23.5468

Table 1 Details of the genome-wide association studies included in this Mendelian randomization analysis

Exposures/Outcomes	Consortium	Ethnicity	Participants	Number of SNPs
Vitamin D	United Kingdom Biobank	European	496946	6896093
Vitamin K	CHAGRE	European	2138	/
Vitamin E	ATBC&PLCO&NHS	European	7781	/
Vitamin A	ATBC&PLCO&NHS	European	7778	/
Vitamin B12	SIID	European	45576	/
Polycystic ovarian syndrome	FinnGen Biobank	European	118870	16379676
Hyperlipidaemia	FinnGen Biobank	European	201497	16380389
Obesity	FinnGen Biobank	European	218735	16380465
Insulin resistance	MAGIC	European	37037	2435028

SNPs: Single nucleotide polymorphisms.

Citation: Shen JY, Xu L, Ding Y, Wu XY. Effect of vitamin supplementation on polycystic ovary syndrome and key pathways implicated in its development: A Mendelian randomization study. World J Clin Cases 2023; 11(23): 5468-5478
URL: https://www.wjgnet.com/2307-8960/full/v11/i23/5468.htm
DOI: https://dx.doi.org/10.12998/wjcc.v11.i23.5468