Meta-analysis of outcomes from drug-eluting stent implantation in infrapopliteal arteries

Table 2 Definitions of the outcomes during follow-up extracted from the included studies

Ref.	ACD	MA	TLR	AE	PP
Siablis et al[42], 2009	All-cause death	Amputation above the ankle	Repeated revascularization on the target lesion prompted by deterioration of limb ischemia	NA	Absence of repeated intervention and occlusion detected by angiography in the target lesion
Karnabatidis et al[44], 2011	Same as the topa	NIa	Same as the top	ACD, or MA, or TLR	Same as the top
Scheinert et al[45], 2012	NA	NA	NA	ACD, or MA, or TLR, or RC ≥ 4a	NA
Rastan et al[26], 2012	NA	NA	NA	ACD, or MA, or target vessel revascularization, or myocardial infarction	NA
Bosiers et al[43], 2012	Same as the topa	NA	NI*	NA	Absence of ≥ 50% binary ISR detected by angiographya
Spreen et al[24], 2017	NA	Amputation above the ankle	NA	MA, or target limb revascularization	NA
Konijn et al[25], 2020	Same as the top	NA	NA	NA	NA
Zuzek et al[27], 2022	Same as the top	Amputation above the transmetatarsal	Same as the top	NA	NA

^aData extracted from survival curve presented in the article and thus transformed. ACD: All-cause death; NA: Not available; MA: Major amputation; NI: No information; TLR: Target lesion revascularization; AE: Adverse event; RC: Rutherford classification; PP: Primary patency; ISR: In-stent restenosis.