Systematic review of fibroblastic rheumatism: A case report

Figure 2 Typical pathological images of skin lesions in patients with fibroblast rheumatism. A: Skin biopsy from the finger revealing dermal fibrous hyperplasia, elastic fiber disorder, skin hyperkeratosis, and irregular thickening of the spinous layer; B: Haematoxylin and eosin staining of left foot articular cartilage displaying central cartilage degeneration and necrosis with calcification, along with dermal collagen fiber hyperplasia and spindle cell proliferation; C and D: Histological examination of upper arm scar tissue and synovium, showing collagen fiber hyperplasia, elastic fiber disorder, and spindle cell proliferation; E and F: Palmar aponeurosis biopsy from the right arch demonstrating fibrous hyperplasia with localized spindle cell proliferation (Haematoxylin and eosin, original magnifications: (A: ×200; B: ×200; C: ×200; D: ×400; E: ×40; F: ×200); G and H: Elastica van Gieson staining revealing reduced elastic fibers in the dermis (G: ×200; H: ×400).