Copyright
©The Author(s) 2023.
World J Clin Cases. Jul 16, 2023; 11(20): 4763-4787
Published online Jul 16, 2023. doi: 10.12998/wjcc.v11.i20.4763
Published online Jul 16, 2023. doi: 10.12998/wjcc.v11.i20.4763
Category | Term | Count in gene set | P value | Genes |
GOTERM_BP_DIRECT | GO:0030199: Collagen fibril organization | 10 | 2.08E-08 | COMP, COL3A1, ADAMTS2, FOXC1, COL1A2, COL5A1, COL12A1, COL5A2, SERPINH1, P3H4 |
GO:0051301: Cell division | 20 | 7.76E-08 | CENPW, UBE2C, RCC2, CDCA7, KIF14, NCAPG, NDC80, CDC25B, CDC20, CCNB2, TPX2, CCNB1, PRC1, NUF2, CDK1, NEK2, KIF2C, BUB1, MAD2L1, SPC25 | |
GO:0030198: Extracellular matrix organization | 13 | 2.67E-07 | OLFML2B, MMP7, MMP1, TNFRSF11B, COL3A1, ADAMTS2, COL1A2, COL5A1, COL4A1, COL5A2, COL4A5, COL8A1, COL10A1 | |
GO:0001501: Skeletal system development | 12 | 3.61E-07 | TEAD4, COMP, COL3A1, VCAN, PKDCC, COL1A2, CDH11, COL5A2, COL10A1, TNFRSF11B, HOXA13, HOXC10 | |
GO:0010273: Detoxification of copper ion | 6 | 7.19E-07 | MT2A, MT1M, MT1G, MT1H, MT1X, MT1E | |
GOTERM_CC_DIRECT | GO:0005615: Extracellular space | 61 | 6.57E-14 | PIGR, SPARC, OLFML2B, CXCL8, COL12A1, CXCL17, COMP, VMO1, PLAU, CA2, FAM3B, COL10A1, SOSTDC1, CPXM1, TIMP1, CPA2, CHIA, MMP7, GPX3, GKN1, BGN, GKN2, PGC, PGF, SFRP4, ALDH3A1, VCAN, COL4A1, SCGB2A1, SFRP5, ANOS1, COL4A5, COL8A1, TFF2, TFF1, CELA3B, CPB1, TNFRSF11B, LRP8, SCUBE2, SELENBP1, CST2, CHAD, SPP1, SERPINH1, CKB, APOE, WNT2, CTHRC1, LINGO1, ANGPT2, CKM, SULF1, KLK11, ATP4A, COL3A1, COL1A2, COL5A1, FAP, COL5A2, ADA |
GO:0031012: Extracellular matrix | 21 | 1.06E-11 | LINGO1, OLFML2B, MMP7, MMP1, BGN, TNFRSF11B, COMP, COL3A1, ADAMTS2, VCAN, COL1A2, COL5A1, COL4A1, COL5A2, CHAD, ANOS1, COL4A5, COL8A1, COL10A1, TIMP1, APOE | |
GO:0005576: Extracellular region | 57 | 5.21E-10 | SPARC, OLFML2B, CXCL8, PSCA, COL12A1, AQP4, COMP, LIPF, ADAMTS2, PLAU, FAM3B, COL10A1, OLR1, TIMP1, CPA2, CHIA, MMP7, GPX3, MMP1, GKN1, MAMDC2, BGN, PGF, SFRP4, VCAN, FNDC1, COL4A1, NRG4, ANOS1, COL4A5, COL8A1, TFF1, LY6E, PKDCC, TNFRSF11B, THY1, THBS2, PLA2G7, SCUBE2, PTPRZ1, SPP1, APOE, METTL7A, WNT2, GPIHBP1, CTHRC1, ANGPT2, B3GAT1, GUCA2B, COL3A1, AKR1B10, COL1A2, COL5A1, QPCT, COL5A2, APOC1, CNTN3 | |
GO:0005581: Collagen trimer | 12 | 7.15E-09 | COL3A1, COL1A2, COL5A1, COL4A1, MMP1, COL12A1, COL5A2, SERPINH1, COL10A1, COL4A5, TIMP1, CTHRC1 | |
GO:0000776: Kinetochore | 11 | 4.23E-06 | CENPW, NUF2, HJURP, KIF2C, CENPN, NEK2, CENPA, BUB1, NDC80, MAD2L1, SPC25 | |
GOTERM_MF_DIRECT | GO:0005201: Extracellular matrix structural constituent | 14 | 7.23E-09 | SPARC, BGN, THBS2, COMP, COL3A1, COL1A2, COL5A1, COL4A1, COL5A2, ANOS1, COL4A5, COL8A1, COL10A1, CTHRC1 |
GO:0030020: Extracellular matrix structural constituent conferring tensile strength | 9 | 1.87E-08 | COL3A1, COL1A2, COL5A1, COL4A1, COL12A1, COL5A2, COL10A1, COL4A5, COL8A1 | |
GO:0048407: Platelet-derived growth factor binding | 5 | 5.29E-06 | PDGFRB, COL3A1, COL1A2, COL5A1, COL4A1 | |
GO:0008270: Zinc ion binding | 23 | 4.29E-04 | CPA2, TRIM50, CPB1, MMP7, ADH1C, MMP1, MT1M, ESRRB, MT1X, ESRRG, MYRIP, ADH7, ADAMTS2, MT2A, CA2, QPCT, MT1G, ZNF385B, CPXM1, MT1H, TIMP1, ADA, MT1E | |
GO:0004111: Creatine kinase activity | 3 | 0.001918971 | CKMT2, CKM, CKB |
- Citation: Yin LK, Yuan HY, Liu JJ, Xu XL, Wang W, Bai XY, Wang P. Identification of survival-associated biomarkers based on three datasets by bioinformatics analysis in gastric cancer. World J Clin Cases 2023; 11(20): 4763-4787
- URL: https://www.wjgnet.com/2307-8960/full/v11/i20/4763.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v11.i20.4763