Microvesicles with mitochondrial content are increased in patients with sepsis and associated with inflammatory responses

Figure 5 Uptake of microvesicles carrying mitochondrial content by human umbilical vein endothelial cells before and after ultrasonic treatment. Microvesicles (MVs) were isolated from the plasma of patients with sepsis and labelled with MitoTracker Deep Red. A: Human umbilical vein endothelial cells (HUVECs) were incubated with the labelled MVs and treated or not treated with sonication. Nuclei were stained by Hoechst; B: Flow cytometric analysis of HUVECs after incubation with the labelled MVs either treated (blue) or not (red) treated with sonication.