Network pharmacology and molecular docking to explore Polygoni Cuspidati Rhizoma et Radix treatment for acute lung injury

Figure 12  Gene ontology biological process and Kyoto encyclopedia of genes and genomes pathway enrichment analysis. A: The gene ontology Biological process enrichment analysis of 58 targets. The top 25 significantly enriched terms in Biological process; B: The Kyoto encyclopedia of genes and genomes pathway enrichment analysis of 60 targets. The top 8 significant pathways for 60 targets; C: Target-Pathway Network. The orange rounds represent Polygoni Cuspidati Rhizoma Et Radix-related targets. The node size is proportional to the target degree in the network. The green round rectangles represent the related pathways. TNF: Tumor necrosis factor; NOD: NOD-like receptor; NF-kappa B: Nuclear factor kappa-B; HIF: Hypoxia-inducible factor-1.