Application of advanced platelet-rich fibrin for through-and-through bony defect during endodontic surgery: Three case reports and review of the literature

Figure 3 Periapical endodontic surgery on the maxillary right lateral incisor advanced platelet-rich fibrin membrane. A: The cone-beam computed tomography (CBCT) shows a well-defined radiolucency surrounding the apex of the maxillary right lateral anterior in the sagittal section. The lesion appears to be perforating the labial and palatal bone surrounding the apex in the coronal section. The root canal appears to be adequate and uniform in density; B: The CBCT shows the bone formation and healing surrounding the apex and bony defect within four months post-operatively in the coronal and sagittal section; C: A clinical photo shows the resected surface of the root and the bony defect; D: The placement of bone graft mixed with the blood clot; E: The platelet-rich fibrin membrane is used to seal the defect and hold the bone graft in place.