Hypoperfusion context as a predictor of 28-d all-cause mortality in septic shock patients: A comparative observational study

Table 4 Area under the curve to predict 28-d mortality for various perfusion markers at specified intervals

Test result variable	Area	Std. Error	P value	Asymptomatic 95%CI
				Lower bound	Upper bound
Lactate at 0 h	0.587	0.058	0.133	0.499	0.671
Lactate at 3 h	0.776	0.048	< 0.001a	0.696	0.843
Lactate at 6 h	0.845	0.04	< 0.001a	0.772	0.902
Lactate clearance at 3 h	0.754	0.053	< 0.001a	0.672	0.824
Lactate clearance at 6 h	0.834	0.041	< 0.001a	0.76	0.893
CRT at 0 h	0.623	0.056	0.028a	0.536	0.705
CRT at 3 h	0.768	0.047	< 0.001a	0.688	0.837
CRT at 6 h	0.757	0.054	< 0.001a	0.675	0.827
ScvO2 at 0 h	0.630	0.062	0.035a	0.542	0.711
ScvO2 at 3 h	0.562	0.064	0.325	0.474	0.648
ScvO2 at 6 h	0.565	0.072	0.367	0.476	0.651
P(cv-a)CO2 at 0 h	0.627	0.060	0.033a	0.540	0.709
P(cv-a)CO2 at 3 h	0.754	0.052	< 0.001a	0.673	0.824
P(cv-a)CO2 at 6 h	0.736	0.060	< 0.001a	0.652	0.808

^aDenotes statistical significance.

CI: Confidence interval; CRT: Capillary refill time; P(cv-a)CO₂: Central venous-arterial pCO₂ gradient; ScvO₂: Central venous oxygen saturation.