Dexmedetomidine-induced anesthesia in elderly patients undergoing hip replacement surgery

Table 3 Comparison of renal function between two groups (mean ± SD)

Group	n	KIM-1 (ng/L)	BUN (ng/L)	Cr (μmol/L)
Preoperative
Control group	49	16.27 ± 5.11	5.20 ± 1.29	76.15 ± 11.09
Observation group	49	16.83 ± 4.07	5.29 ± 1.26	75.56 ± 12.59
t value	-	0.361	0.130	0.062
P value	-	0.549	0.720	0.804
Intraoperative
Control group	49	28.22 ± 6.55a	6.98 ± 1.22a	95.52 ± 11.51a
Observation group	49	21.09 ± 5.55a	6.07 ± 1.13a	91.12 ± 13.30a
t value	-	33.745	14.779	3.976
P value	-	< 0.001	< 0.001	0.049
6 h after operation
Control group	49	89.55 ± 8.55a,d	6.08 ± 1.23	86.05 ± 10.34a,d
Observation group	49	52.50 ± 6.76a,d	5.98 ± 1.13	81.25 ± 11.36a,d
F value	-	566.402	0.197	4.787
P value	-	< 0.001	0.658	0.031

^aP < 0.05 vs preoperative.

^dP < 0.05 vs intraoperative.

KIM-1: Serum kidney injury molecule-1; BUN: Urea nitrogen; Cr: Creatinine.