Dexmedetomidine-induced anesthesia in elderly patients undergoing hip replacement surgery

Table 2 Comparison of serum inflammatory factor levels between the two groups (mean ± SD, ng/L)

Group	n	CRP	TNF-α	IL-1β
Preoperative
Control group	49	3.33 ± 1.21	15.11 ± 4.20	173.55 ± 23.52
Observation group	49	3.15 ± 1.20	15.50 ± 4.03	173.15 ± 22.50
F value	-	0.562	0.220	0.086
P value	-	0.455	0.640	0.932
Intraoperative
Control group	49	15.53 ± 4.22a	53.23 ± 8.12a	199.25 ± 22.10a
Observation group	49	7.25 ± 3.20a	31.20 ± 5.21a	190.23 ± 21.33a
F value	-	119.785	255.597	4.222
P value	-	< 0.001	< 0.001	0.043
6 h after operation
Control group	49	18.25 ± 4.13a,d	60.27 ± 9.23a,d	293.25 ± 11.50a,d
Observation group	49	11.73 ± 2.50a,d	38.25 ± 8.20a,d	203.19 ± 12.37a,d
F value	-	89.449	156.076	1393.312
P value	-	< 0.001	< 0.001	< 0.001

^aP < 0.05 vs preoperative.

^dP < 0.05 vs intraoperative.

CRP: C-reactive protein; TNF-α: Tumor necrosis factor-alpha; IL-1β: Interleukin-1β.