Co-existing squamous cell carcinoma and chronic myelomonocytic leukemia with ASXL1 and EZH2 gene mutations: A case report

Figure 1 Morphological and biopsy results of chronic myelomonocytic leukemia bone marrow analysis. A: Pelger deformed granules (100× magnification), exhibiting abnormal proliferation of monocytes and occasional naïve monocytes (with well-differentiated monocytes accounting for 45% of total monocytes), inhibited erythroid hyperplasia, three megakaryocytes, and rare platelet; B: Increased naïve-stage cells, with an increased granulocyte-to-nucleated red blood cell ratio. The granular lineage predominantly comprised intermediate (lower-stage) and visible monocytes, based on reticulocyte staining (MF-0 grade; ×4 and ×40 magnification).