Clinical infections in neurosurgical oncology: An overview

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May 26, 2023 (publication date) through Dec 22, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. May 26, 2023; 11(15): 3418-3433
Published online May 26, 2023. doi: 10.12998/wjcc.v11.i15.3418

Table 2 Specific factors affecting the course of central nervous system infections

Factor	Effect
Blood-brain barrier	Selective permeability to chemotherapeutic agents (affecting the infection course)
Uniformity of the subarachnoid space	Allows continuous spread of infection through the cerebrospinal fluid
Circulatory disturbances	Ischaemia from venous and arterial infarctions
Increased intracranial pressure	Vessel compression and thrombosis
Cerebral oedema	Leads to increase in intracranial pressure, potentiating brain damage

Citation: Velnar T, Kocivnik N, Bosnjak R. Clinical infections in neurosurgical oncology: An overview. World J Clin Cases 2023; 11(15): 3418-3433
URL: https://www.wjgnet.com/2307-8960/full/v11/i15/3418.htm
DOI: https://dx.doi.org/10.12998/wjcc.v11.i15.3418