Implications of obesity and adiposopathy on respiratory infections; focus on emerging challenges

Figure 1 Obesity impacts host-defence against respiratory infections, including direct physiological/mechanical impacts on lung functions but also notably adipose tissue dysfunction, a chronic low grade inflammatory status and potentially blunted immune system responses. ER: Endoplasmic reticulum; IL: Interleukins; MCP-1: Monocyte chemoattractant protein-1; OSAS: Obstructive sleep apnoea syndrome; TNF-α: Tumour necrosis factor alpha. Parts of the figure were drawn by using pictures from Servier Medical. Smart. [cited 3 February 2023]. Available from: smart.servier.com.