Association of C-reactive protein and complement factor H gene polymorphisms with risk of lupus nephritis in Chinese population

Table 3 Association of C-reactive protein haplotypes with risk of lupus nephritis

CRP haplotype		SLE-freq (%, n = 270)	Normal-freq (%, n = 303)	χ2	Overall P value
H1	G G G G T A	17.8	16.7	3.293	0.655
H2	T A G C G A	4.3	5.1
H3	T A G G G A	50.2	52.8
H4	T G A G A A	5.4	5.6
H5	T G G G G A	4.1	5.1
H6	T G G G G G	16.6	13.7

Single nucleotide polymorphism order in the haplotypes is arranged according to their positions in the chromosome (rs3093077, rs1205, rs1130864, rs1800947, rs3091244, rs2794521). Only the significant haplotypes (frequency > 3.0%) are shown. CRP: C-reactive protein; SLE: Systemic lupus erythematosus.