Association of C-reactive protein and complement factor H gene polymorphisms with risk of lupus nephritis in Chinese population

Table 1 Genotype and allele frequencies of C-reactive protein single nucleotide polymorphisms, n (%)

Genotype	LN	Normal	P value	Allele	LN	Normal	P value
rs1205 (C>T)
CC	53 (19.63)	49 (16.17)	0.469	C	245 (45.37)	254 (41.91)	0.239
CT	139 (51.48)	156 (51.49)		T	295 (54.63)	352 (58.09)
TT	78 (28.89)	98 (32.34)
rs3093077 (A>C)
AA	173 (64.07)	208 (68.65)	0.436	A	436 (80.74)	502 (82.84)	0.358
AC	90 (33.33)	86 (28.38)		C	104 (19.26)	104 (17.16)
CC	7 (2.59)	9 (2.97)
rs3091244 (C>T>A)
CC	153 (56.67)	180 (59.41)	0.9351	C	410 (75.93)	467 (77.06)	0.712
CT	23 (8.52)	28 (9.24)		T	29 (5.37)	36 (5.94)
CA	81 (30.00)	79 (26.07)		A	101 (18.70)	103 (17.00)
TT	1 (0.37)	1 (0.33)
TA	4 (1.48)	6 (1.98)
AA	8 (2.96)	9 (2.97)
rs1130864 (G>A)
GG	241 (89.26)	270 (89.11)	0.7971	G	509 (94.26)	572 (94.39)	0.924
GA	27 (10.00)	32 (10.56)		A	31 (5.74)	34 (5.61)
AA	2 (0.74)	1 (0.33)
rs1800947 (C>G)
CC	245 (90.74)	273 (90.10)	1.0001	C	515 (95.37)	575 (94.88)	0.703
CG	25 (9.26)	29 (9.57)		G	25 (4.63)	31 (5.12)
GG	0 (0.00)	1 (0.33)
rs2794521 (T>C)
TT	187 (69.26)	222 (73.27)	0.177	T	446 (82.59)	520 (85.81)	0.135
TC	72 (26.67)	76 (25.08)		C	94 (17.41)	86 (14.19)
CC	11 (4.07)	5 (1.65)

¹Fisher’s exact test; unmarked, Pearson’s chi-squared test.

LN: Lupus nephritis.