Hepatobiliary system and intestinal injury in new coronavirus infection (COVID-19): A retrospective study

Table 2 Changes of liver/spleen density in patients with coronavirus disease 19, depending on the severity of the disease

Indication	Density, HU		P value
	COVID-19 patients, mild severity (n = 19)	COVID-19 patients, moderate severity (n = 61)
Liver	48.52 (43.7-52.1)	42.63 (39.2-47.8)	< 0.05
Spleen	47.41 (42.1-51.5)	48.78 (43.4-52.8)	0.47
Liver/spleen ratio	1.02 (0.92-1.09)	0.87 (0.69-0.98)	< 0.05

After first CT, the lower of liver density < 45 HU was noted in 28 (34.7%). Patients with moderate severity had significantly lower liver density 42.6 HU (39.2-47.8), compare with patients with mild COVID-19 48.5 HU (43.7-52.1) (P < 0.05). The liver/spleen density ratio was also lower in moderate severity group, 0.87 (0.69-0.98) and 1.02 (0.92-1.09) (P < 0.05) suggest. COVID-19: Coronavirus disease 19; HU: Hounsfield unit; CT: Computed tomography.