Identification of a four-miRNA signature predicts the prognosis of papillary thyroid cancer

Table 4 Univariate and multivariate cox regression analyses of the four miRNA signature and clinicopathologic factors in the entire set

	Univariate analysis		Multivariate analysis
	HR (95%CI)	P	HR (95%CI)	P
Age (< 45 vs ≥ 45)	0.013 (0.000-0.756)	0.036	-	-
Stage (I/II vs III/IV)	0.141 (0.045-0.439)	0.001	-	-
Sex	2.029 (0.734-5.613)	0.173	-	-
Four miRNA signature (high risk vs low risk)	8.625 (1.956-38.03)	0.004	6.186 (1.405-27.24)	0.016

CI: Confidence interval; HR: Hazard ratio.